Quadrant 904 was a region of space in the Milky Way Galaxy. A star desert was located in this quadrant.

In 2267, when the USS Enterprise was first intercepted by the planet Gothos in this area, the ship was eight days distant from Beta VI at warp factor three and Earth was nine hundred light years away. (TOS: "The Squire of Gothos")

In 2328, the Quadrant 904 Central Station was a point of embarkation and destination for commercial transports. (TNG-R: "Inheritance")

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