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Memory Alpha
Multiple realities
(covers information from several alternate timelines)

The Reed family was an Earth family of British descent.

Upon hearing that Reed would go back in time to 1588 if he could pick any time, as it was the year England defeated the Spanish Armada, Trip Tucker felt sure that one of Reed's ancestors was involved. (ENT: "Future Tense")

Several generations of this family served in the Royal Navy on Earth, including Malcolm Reed's father and paternal grandfather, the latter of whom served as an ordnance officer. (ENT: "Silent Enemy", "Shuttlepod One", "Minefield")

This reference to Malcolm Reed's grandfather was originally, as exemplified by the final draft script of "Silent Enemy", to his great-grandfather instead.

His great uncle, an aquaphobe, served as chief engineer aboard the submarine HMS Clement. On a routine patrol, his ship struck a mine left over from a previous world war. As the ship was stuck under an ice shelf, he sealed himself in the engine room, where he kept the reactor online for long enough for his crewmates to escape. When pinned onto the Enterprise's hull by a Romulan mine, Reed recounted this story to Captain Archer. (ENT: "Minefield")

Hoshi Sato once contacted Malcolm's uncle Archie and his two unmarried aunts, in an attempt to find out what food Malcolm liked to eat. Unfortunately, none were able to give her an answer. (ENT: "Silent Enemy")

Malcolm Reed was the first family member who joined Earth Starfleet. (ENT: "Silent Enemy")

As of an alternate timeline 2154 where Enterprise NX-01 was stranded in 2037, Reed's family line ended with him, much to his dismay. He felt certain that on a ship that size, he should have been able to find someone. Hoshi Sato reminded him that only a third of the crew of Enterprise were women, so he ought not to take it personally that he was one of likely many bachelors left over. (ENT: "")


It is unknown if Sherry is one of the two unnamed 'spinster aunts'.
In the script of "Silent Enemy" (set in 2151), Stuart and Mary Reed are described thus; "They're in their 60's, British."
In a never-produced ENT story, a great-grandfather of Malcolm and Madeline Reed was to have been linked to Colonel Green. ("Observer Effect" audio commentary, ENT Season 4 Blu-ray special features)