Resistance may refer to:
- Disease resistance, the ability to resist diseases
- Resistance movement, a group leading an uprising
- Active resistance, a form of defense that involves violence
- Passive resistance, a form of defense that avoids violence
- Resistance cell, a part of a resistance organization
- Resistance fighter, a member of a resistance movement
- Resistance quotient, a Borg measurement
- Real world
- "Resistance", the second season Voyager episode
- Resistance (novel), the post-Nemesis TNG novel
- "Resistance (photonovel)", a comic/photonovel released by IDW
- Resistance Is Futile: Assimilating Star Trek - The Next Generation
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