In the 24th century, Lwaxana Troi, daughter of the Fifth House of Betazed, was holder of the Sacred Chalice of Rixx – something she never failed to mention in formal introductions. (TNG: "Haven", "Half a Life"; DS9: "The Forsaken")
However, in a private conversation between Deanna Troi and Lwaxana in 2366, Deanna stated dismissively that the Sacred Chalice of Rixx was merely "an old clay pot with mold growing inside it." (TNG: "Ménage à Troi")
In the novel Q-in-Law by Peter David, Lwaxana admits, in private conversation with Q, that the Sacred Chalice is a "pointless clay pot," and that caring for it is one of several routines she undertakes to sublimate her anxiety over Deanna serving in deep space with Starfleet.
According to the short story "The Ceremony of Innocence is Drowned" by Keith R.A. DeCandido, collected in the anthology Tales of the Dominion War, the Sacred Chalice of Rixx was destroyed, along with the Holy Rings of Betazed, when Lwaxana Troi's home was leveled during the Dominion invasion of Betazed.