Sausalito was a city in the San Francisco Metropolitan Area, California. In 1986, its location was labeled on a MUNI map. In that same year, it was home to the Cetacean Institute. (Star Trek IV: The Voyage Home)
In 2139, Charles Tucker III lived in Sausalito near the Vulcan Compound – a Vulcan residential and diplomatic facility located in the town. (ENT: "Broken Bow") While stationed in this city, T'Pol went on a five-day leave to Carbon Creek, Pennsylvania. (ENT: "Carbon Creek")
In 2152, Tucker mused about the possibility of an Earth colony named "New Sausalito" existing in the near future. (ENT: "Shockwave")
After escaping prison in San Francisco sometime prior to May 2154, Arik Soong made it to Sausalito before the authorities recaptured him – a feat he was "particularly proud of". (ENT: "Borderland")