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Sector 22358 was a region of space. This sector was located in the region between Sectors 21538 and 23079.

In 2369, according to a starship mission status chart seen in the observation lounge of the USS Enterprise-D, the USS Repulse was assigned to deep space exploration of this sector. (TNG: "Chain of Command, Part I", display graphic)

This sector was only mentioned in writing.
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