Sector 441 was an area of space in the Alpha Quadrant. This sector, containing the anomalous Briar Patch, was located in Federation space.
The Briar Patch contained the stars SNC 461206, UFC 8177, and the Ba'ku system, which was home to the inhabited planet Ba'ku. Outside the Briar Patch were SNR 093120, UFC 9364, NGC 2812 and QSR 390021.
Though not mentioned in dialogue, the star chart was depicted legibly in The Secrets of Star Trek: Insurrection (p. 143).
In 2154, Arik Soong, who, along with a group of Human Augments, had stolen a Klingon Bird-of-Prey, set course for Sector 441, where he felt the Briar Patch, known by the Klingons as "Klach D'Kel Brakt," would provide a safe place for the incubation and maturation of several augment embryos which he had stolen from Cold Station 12. (ENT: "The Augments")
In 2375, the USS Enterprise-E traveled to Sector 441 in order to investigate a mysterious malfunction of Lieutenant Commander Data, who was participating in an anthropological expedition on a planet located in the Patch. (Star Trek: Insurrection)