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Sector 52 was a region of space. Sector 052/32 included a part of the Romulan Neutral Zone.

In 2364, the Federation starships USS Tranquillity Base, USS Max Plank, and USS Non Sequitur and the starbase Starbase Trailer Twenty-Nine were ordered by Starfleet Command to increase sensor drone surveillance of this sector. This sector was mentioned in mission orders. (TNG: "Conspiracy", okudagrams)

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