Multiple realities
(covers information from several alternate timelines)
A shopkeeper, or storekeeper, was an individual who owned and operated a shop.
During an away mission on the Akaali homeworld in 2151, T'Pol suggested to talk to the shopkeeper of a curio shop first before beaming an Akaali aboard for studying. (ENT: "Civilization")
Doctor Beverly Crusher almost bought fabric from a Bandi shopkeeper on Farpoint Station in 2364. (TNG: "Encounter at Farpoint")
Deep Space 9 had many shopkeepers, including mostly Bajorans, a female Bolian, and a Cardassian. (DS9: "In the Hands of the Prophets", "The Way of the Warrior", "Image in the Sand")
In an alternate timeline, a shopkeeper in the Delta Quadrant attempted to sell a timepiece to Tom Paris. (VOY: "Time and Again")