Spatial orientation was one's ability to make sense of the shape and size of an area and adjust accordingly.
In 2371, after Nog failed the spatial orientation test portion of the Starfleet Academy entrance exam, Rom shared his son's confusion as to how Nog could have failed. He recalled that the boy had always been good with spatial orientation, giving the example of a time when they re-did the floors at Quark's. Nog had managed to stack all the chairs so that they would fit behind the bar. (DS9: "Facets")