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Lieutenant Spinelli was a male Human Starfleet officer who lived during the mid-23rd century. He served in the command division aboard the USS Enterprise under Captain James T. Kirk, during Kirk's historic five-year mission. He was assigned as one of the ship's helmsmen in 2267.

That same year, Spinelli was one of a few Enterprise officers privileged to dine with the late 20th century tyrant Khan Noonien Singh. Spinelli was later among the crew trapped on the bridge when Khan attempted to take over the ship. Spinelli passed out after the life support to the bridge was cut. Later, he was seated in a prisoner's row in the briefing room, forced to watch while Khan had Captain Kirk tortured in the decompression chamber, which was shown on the room's viewscreen. Afterward, Spinelli, along with several Enterprise crewmembers, were knocked unconscious when Kirk and Spock had the briefing room and almost all decks flooded with anesthesia gas in order to retake the ship. (TOS: "Space Seed")

Lt. Spinelli was portrayed by actor Blaisdell Makee, who later portrayed Singh.
He was mentioned in the comics story "For Whom the Bell Tolls", part of DC Comics' The Modala Imperative series.

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