Multiple realities
(covers information from several alternate timelines)

St. Louis was a city in Missouri.

In an alternate timeline in which Nazi Germany had invaded the United States, as of 1944, St. Louis was controlled by American forces. (ENT: "Storm Front", "Storm Front, Part II")

In 2257, Ensign Sylvia Tilly owned two St. Louis-themed snow globes, featuring the Gateway Arch, which were on display in her quarters on the USS Discovery. (DIS: "Such Sweet Sorrow")

Years before her assignment to the USS Enterprise-D, Beverly Crusher studied tap and jazz dance at the Saint Louis Academy, winning several [award]s, through which she became known as "The Dancing Doctor." (TNG: "Data's Day")

St. Louis was named on a map of the United States (Die Vereinigten Staaten von Amerika).
St. Louis is also the real-world hometown of Scott Bakula, who portrayed Captain Jonathan Archer on Star Trek: Enterprise.

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