Starbase 416 was a Federation starbase administered by Starfleet. This was a planetside base with a medical facility capable of treating victims of cove palm parasite. The base was near Ogus II.

In 2367, the USS Enterprise-D rushed to Starbase 416 in order to treat young Willie Potts, who had accidentally ingested the cove palm fruit while on Ogus II. (TNG: "Brothers")

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