During a second contact mission with the Galardonians in 2380, the Cerritos became infected by a rage virus brought back by Commander Jack Ransom, who was bitten by a Galardonian insect. This quickly resulted in an outbreak that consumed much of the ship. When the away team returned from the second contact mission, T'Ana noticed that Ensign Brad Boimler was covered in slime that he got from being suckled by a Galardonian spider cow. T'Ana discovered that the slime was able to completely neutralize the rage virus, and was able to synthesize a cure from the substance, returning everyone to normal. (LD: "Second Contact")
T'Ana tutored Ensign Sam Rutherford, who was exploring the medical division. Initially, she was impressed with his performance in managing medical equipment, but was disappointed with his bedside manner after he failed to keep a patient distracted. T'Ana dismissed Rutherford, and recommended trying out the security division. (LD: "Envoys")
On stardate 57538.9, T'Ana and the other senior officers were gathered in the conference room to witness Ensign Beckett Mariner's promotion to lieutenant before moving on to debates over new conference chairs. She later joined the senior staff, including Mariner, in a game of poker. (LD: "Moist Vessel")
During a salvage mission of a pair of wrecked cargo ships, T'Ana was in the mess hall eating nachos when Mariner accidentally bumped into her, causing her to fall face-first into her food. T'Ana furiously scolded Mariner, noting how difficult it was to clean nacho cheese out of her fur in a sonic shower. Mariner tried to apologize, but T'Ana remained angry with her. She started noting her past insubordinate behavior, and said she should work at Starbase 80 if she wanted to goof around. Before the situation escalated any further, Ensign Fletcher intervened, and was able to calm things down by giving T'Ana a warm towel and a new platter of nachos.
When the Cerritos was on the verge of destruction during a standoff with Drookmani scavengers, T'Ana advised the crew to be evacuated before they noticed the Drookmani ship was being dismantled by a corrupted isolinear core. In the heat of their victory, Lieutenant Shaxs pulled T'Ana in for a kiss, which she seemingly enjoyed. (LD: "Terminal Provocations")
T'Ana and Shaxs shared some feelings for one another while they served together. When the Cerritos defeated a Drookmani scavenger ship, Shaxs celebrated on the bridge by giving her a kiss at his station, which she enjoyed. Later, after she found out that Mariner was Freeman's daughter, she asked Mariner if she thought that Freeman would be okay with her starting a relationship with Shaxs. Unfortunately, a short time later, Shaxs sacrificed his life to save the Cerritos, and this relationship never came to pass. (LD: "Terminal Provocations", "No Small Parts")
- - T'Ana and Ensign D'Vana Tendi, during a surgery on Lieutenant Commander Stevens. (LD: "Second Contact")
"Listen kid, you're great at digging around in a body. But if you can't muster up some bedside manner, you may as well be with the grunts in security."
- - T'Ana and Mariner, after the latter declined the former's offer of eliminating her scars. (LD: "Temporal Edict")
"Do you know how hard it is to get cheese out of fur in a sonic shower?!"
"We could do uh evasive maneuver eighty...eight?"
"Is he *bleep* serious?"
"You think your mom would be okay with me and Shaxs making a little love connection? I'd love to snag that Bajoran beefsteak with my coital hooks."
- - T'Ana, asking Mariner if Freeman would be okay with her and Shaxs starting a relationship. (LD: "No Small Parts")
T'Ana was voiced by Gillian Vigman.