(written from a Production point of view)
Gerrold, then a twenty-two year-old college student majoring in theater arts, relates how, after watching the premiere episode, "The Man Trap" on September 8, 1966, he immediately sat down and began a sixty-page outline entitled "Tomorrow Was Yesterday", which concerned the Enterprise discovering a "generation" ship. He managed to get an agent to submit it to Star Trek, and though Gene L. Coon rejected it as being too expensive to film, he was impressed with Gerrold's writing ability and invited him to visit his office to talk. Although Star Trek was already booked up on episodes for the first season, Coon expressed a willingness to take pitches for second season episodes.
When Gerrold met with Coon he pitched at least five story lines – among them, "Bandi", "The Protracted Man", and "The Fuzzies". Coon initially rejected them all, but a while later called Gerrold's agent and said he wanted to talk to Gerrold about his "Fuzzies" idea.
After Coon expressed interest in the premise, Gerrold wrote the outline, now entitled "A Fuzzy Thing Happened To Me..." Coon eventually bought the outline, and Gerrold scripted it as "The Trouble with Tribbles".
This book details the writing process, the filming, and the various rewards that have come Gerrold's way as a result of the episode. It also touches on the similarities between the tribbles and the proliferating Martian Flat Cats in Robert A. Heinlein's 1952 novel The Rolling Stones. The book also includes the script of the episode, with annotations and commentary by Gerrold.
While its predecessor, The Making of Star Trek, is seen as the first book dedicated to the production of a TV series, The Trouble with Tribbles stands as the first book dedicated to the production of a single television episode. The inclusion of the script marked the first time a complete script for Star Trek had been published.