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T'Pol and Phlox exposed to theta radiation in the decon chamber

Theta radiation was a form of energy which can be extremely toxic to humanoid life. A regular byproduct of antimatter waste, theta radiation in high enough concentrations can disrupt subspace and prevent the formation of a stable warp field. (VOY: "Night", "Juggernaut")

Arithrazine was a medication used for the most extreme cases of theta radiation poisoning. (VOY: "The Omega Directive")

In the absence of proper precautions, theta radiation could be extremely hazardous. Symptoms of theta radiation poisoning included hallucinations, fatigue, and nausea. Over longer periods of time, cumulative exposure could cause cellular degradation and severely shorter life expectancy, and theta radiation of extremely high levels could liquefy organic material. (VOY: "Night", "Juggernaut", "Life Line")

By the 24th century, Starfleet had eliminated the generation of this form of waste product, utilizing a transkinetic chamber to break down the residual antimatter on a subatomic level, and a series of radiometric converters to absorb the resultant theta radiation, recycling the energy and using it to power various ships' systems. (VOY: "Night")

In 2063, upon traveling back in time from the year 2373, the Borg attacked Zefram Cochrane's launch facility in Montana, damaging, among other things, the throttle assembly of Cochrane's warp vessel, the Phoenix, causing it to leak harmful theta radiation. This necessitated the inoculation of members of the crew of the USS Enterprise, which had followed the Borg vessel from the future, against theta radiation poisoning. Cochrane's partner, Lily Sloane, herself succumbed to the effects of severe theta radiation poisoning, although she was successfully treated by Doctor Beverly Crusher, chief medical officer of the Enterprise. (Star Trek: First Contact)

Theta radiation in small doses could be used to destroy microorganisms, and was used in Enterprise NX-01's decontamination chamber when it was determined that a member of the crew was infected. In 2153, after exploring an uninhabited planet, Doctor Phlox discovered that he and Sub-Commander T'Pol had been infected with an unknown microorganism, and attempted to use theta radiation to eliminate the infection. (ENT: "Bounty")

Later that year, while attempting to synthesize trellium-D with which to insulate their hull against the effects of spatial anomalies, T'Pol and Commander Tucker attempted theta radiation bombardment. However, when the molecular pressure began to rise uncontrollably, Tucker deactivated the theta radiation, to no effect, eventually necessitating Tucker and T'Pol's evacuation of the lab in order to avoid the resultant explosion. (ENT: "Rajiin")

A Malon vessel vents a theta radiation cloud

In 2375, while traversing the Delta Quadrant, the crew of the USS Voyager encountered a region of space nearly 2,500 light years across, wherein no star systems existed, and all light from outside was occluded by heavy concentrations of theta radiation, resulting in a starless, oppressive expanse which the crew took to calling "the Void" The crew soon discovered that the theta radiation was a result of massive amounts of antimatter waste being dumped in the region by the crew of a Malon export vessel, eleventh gradient, despite the harmful effects it was having on at least one species native to the area. In an attempt at diplomacy, the Voyager crew offered to share their reclamation technology with Controller Emck, the master of the Malon vessel, although Emck ultimately chose to turn down their offer, as it would put him out of business. (VOY: "Night")

Later that year, the Voyager crew encountered another Malon vessel, while attempting to retrieve a multi-spatial probe which had become trapped in the atmosphere of a gas giant. The Malon, attempting to obtain the probe for themselves, released a cloud of theta radiation as a form of attack, successfully weakening Voyager's shields to 89 percent. (VOY: "Extreme Risk")

Also that year, while attempting to narrow the possible events which could have been causing a ship-wide molecular decay, the biomimetic crew of a duplicate Voyager considered an encounter with a species known as the Kmada, who attempted to sabotage their life support system with theta radiation, although they ultimately rejected this as a possibility. (VOY: "Course: Oblivion")

Later in 2375, Voyager encountered a Malon vessel yet again, this time suffering from catastrophic damage, threatening to explode and spread over four trillion isotons of antimatter waste over an area of three light years. Utilizing an inoculation developed by The Doctor which temporarily prevented their cells from absorbing theta radiation (although Neelix swore by his recipe of crushed rama leaves and Katyllian cloves), a boarding party from Voyager attempted to repair the vessel, only to discover that the ship had been sabotaged by what the Malon referred to as a "vihaar," a former crewmember who had been severely poisoned and deformed by exposure to theta radiation. (VOY: "Juggernaut")

In 2376, during his initial examination of Dr. Lewis Zimmerman, The Doctor asked him if he had been exposed to theta radiation, provoking annoyance from Zimmerman who considered it the sort of question a first-year medical student would ask. (VOY: "Life Line")

The class Y planet Theta Zeta in the Verubin Nebula was surrounded by a number of extremely dangerous radiations, including type 9 and type 10 theta radiation (magnitude gamma). (DIS: "Su'Kal")

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