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A thought was an idea or concept created by the mental activity of the mind. The process of creating a thought was called thinking.

The Talosians of Talos IV could read the thoughts of their specimens. After reading Vina's thoughts, as well as her feelings and her dreams of what would be a perfect man, the Talosians picked Captain Christopher Pike. Furthermore, the Talosians could create an illusion out of a individual's thought for them to experience, such as the crew of the USS Enterprise thinking they had found the survivors from the crashed SS Columbia. (TOS: "The Cage")

According to Spock in 2267, Jackson Roykirk's dream was to build a perfect thinking machine, capable of independent logic. The result was the prototype Nomad, the best thinking machine that could be engineered which was lauched in the early 2000s. (TOS: "The Changeling")

The Traveler claimed thought was the basis of all reality. (TNG: "Where No One Has Gone Before")

Sentient species, such as Humans, have the ability to distinguish between thought and reality. (TNG: "Where No One Has Gone Before")

Q once said to Captain Jean-Luc Picard that he "thought by now you would have scampered back to your own little star system." (TNG: "Hide and Q")

Telepathic Lwaxana Troi was forced to terminate the employment of her valet, Mr. Xelo, because he was strongly attracted to her and his thoughts became truly pornographic. (TNG: "Haven")

In 2364, despite the holographic Minuet being a computer-generated image, the things she thought were among her aspects which seemed so real to William T. Riker. (TNG: "11001001")

In most Betazoids, their telepathic gifts developed at adolescence, however, occasionally a child was born with their telepathic abilities switched on. Most Betazoids born that way never led a normal life as the noise of other peoples' thoughts and feelings were overwhelming, incomprehensible, and painful, especially to a child. (TNG: "Tin Man")

In the 2330s, at Omicron Theta colony, Doctor Noonien Soong scanned the synaptic patterns of the colonists' temporal lobes and programmed them into Data's neural nets. As a result, Data could have been said to have possessed, to a degree, their thoughts. (TNG: "Silicon Avatar")

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