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The throat was a part of the neck of many humanoid species, beginning at the back of the mouth down to the stomach, and played a key role in breathing and ingestion.

In 2267, held at scalpel-point by Khan Noonien Singh, Doctor Leonard McCoy suggested he make up his mind whether he was going to choke him or cut his throat. After Khan asked McCoy where he was, McCoy quipped, "You're in bed, holding a knife at your doctor's throat." (TOS: "Space Seed")

In 2285, when Khan Noonien Singh arrived at Regula in the USS Reliant, he slit the throats of most of the personnel of Regula I. (Star Trek II: The Wrath of Khan)

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