At the outbreak of the Dominion War in 2373, a task force comprised of Starfleet and Klingon forces attacked and destroyed the shipyards while Dominion forces were occupied attacking Deep Space 9. Starfleet chose to launch an attack on the shipyards rather than send reinforcements to Deep Space 9, which was lost to the Dominion. However, DS9 personnel were able to establish a minefield at the mouth of the wormhole prior to being forced from the station, which severed the Dominion's supply line from their home territory in the Gamma Quadrant.
The destruction of the shipyards at Torros III, together with the mining of the Bajoran wormhole, was an early blow to the Dominion war effort in the Alpha Quadrant. Even so, the Dominion was able to launch a successful campaign into Federation territory. (DS9: "Call to Arms")