Trilithium resin spreading through the atmosphere of Solosos III.

Trilithium resin was a highly toxic waste product that was produced by the engines of Starfleet vessels in the 24th century. It could be produced from trilithium, and might simply be called that. A volatile substance, it's only possible use was as a weapon. Storing and moving it was a very delicate process and required specialized equipment. (TNG: "Starship Mine"; DS9: "For the Uniform")

In 2369, a group of weapons dealers led by Kelsey attempted to steal trilithium resin for later sale to terrorists from the warp core of the USS Enterprise-D while it was undergoing a baryon sweep at Arkaria Base. They were stopped by Captain Jean-Luc Picard. (TNG: "Starship Mine")

Trilithium resin was also had the effect of rendering a planet uninhabitable to Humans (but not Cardassians) when dispersed through the planet's atmosphere by a quantum torpedo detonation. Four hundred kilograms of trilithium used in this manner was enough to make a planet uninhabitable to Humans for fifty years. Captain Benjamin Sisko poisoned the atmosphere of Solosos III with trilithium resin in 2373 in response to Michael Eddington's use of cobalt diselenide, a biogenic weapon. (DS9: "For the Uniform")

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