Trilithium resin spreading through the atmosphere of Solosos III.

Trilithium resin was a highly toxic waste product that was produced by the engines of Starfleet vessels in the 24th century. It could be produced from trilithium, and might simply be called that. A volatile substance, it's only possible use was as a weapon. Storing and moving it was a very delicate process and required specialized equipment. (TNG: "Starship Mine"; DS9: "For the Uniform")

In 2369, a group of weapons dealers led by Kelsey attempted to steal trilithium resin for later sale to terrorists from the warp core of the USS Enterprise-D while it was undergoing a baryon sweep at Arkaria Base. They were stopped by Captain Jean-Luc Picard. (TNG: "Starship Mine")

Trilithium resin was also produced when Quantum torpedoes carrying trilithium were detonated in an atmosphere, which made that planet lethal to Humans (but not Cardassians). Four hundred kilograms of trilithium used in this manner was enough to make a planet uninhabitable to Humans for fifty years. Captain Benjamin Sisko poisoned the atmosphere of Solosos III with trilithium resin in 2373 in response to Michael Eddington's use of cobalt diselenide, a biogenic weapon. (DS9: "For the Uniform")

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