The USS Biko was a 24th century Federation Oberth-class starship operated by Starfleet.

In 2369, the supply ship rendezvoused with the USS Enterprise-D at Deinonychus VII after an initial delay of forty-eight hours. (TNG: "A Fistful of Datas")

The Star Trek Encyclopedia (4th ed., vol. 1, p. 83) stated the ship was "named for Steven Biko, South African civil rights activist, martyred in 1977."
The Star Trek Encyclopedia (4th ed., vol. 2, p. 327) gave the registry number of this vessel as NCC-50331 and incorrectly identified it as an Olympic-class starship.
For the appearance of the Biko, stock footage of the USS Cochrane from "The Drumhead" was used, with a planetary backdrop added. The footage includes the registry number.

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