The USS Drake was a Federation starship that was in service during the late 24th century.
During the brief Federation-Klingon War in 2373, the Drake was ambushed by Klingon forces and was severely damaged before escaping for repairs at Deep Space 9. (DS9: "Apocalypse Rising")
- According to the Star Trek Encyclopedia, this starship was an Andromeda-class starship, with the registry NCC-70956. It was the successor of the Wambundu-class USS Drake.