The USS Drake was a Federation starship that was in service during the late 24th century.

During the brief Federation-Klingon War in 2373, the Drake was ambushed by Klingon forces and was severely damaged before escaping for repairs at Deep Space 9. (DS9: "Apocalypse Rising")

According to the Star Trek Encyclopedia, this starship was an Andromeda-class starship, with the registry NCC-70956. It was the successor of the Wambundu-class USS Drake.
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