USS Excelsior may refer to:
- USS Excelsior (NCC-0220), an Excelsior-type starship
- USS Excelsior (NCC-2000), an Excelsior-class prototype
- USS Excelsior (NCC-27445), a mid-24th century starship
- USS Excelsior (NCC-42037), an early 25th century Excelsior II-class starship
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