The Unroth system was a planetary system in the Beta Quadrant. The system's primary was named Unroth.
In 2256, this star's location was labeled on the star chart "Alpha/Beta Quadrant Overview" in the ready room aboard the USS Discovery. (DIS: "Magic to Make the Sanest Man Go Mad")
In 2257, during the first Federation-Klingon War, this star's system was occupied by the Klingons. (DIS: "The War Without, The War Within")
By the late 24th century, this system was located along the Cardassian-Romulan border. As 2375, a Romulan colony existed in the Unroth system. Later that year, the Breen military leader Thot Gor observed that the colony's long range sensor array was being repaired, leaving them vulnerable to attack. This insight had previously eluded Dominion strategists. (DS9: "Strange Bedfellows")