West was a compass direction, opposite to east.

In 2270, Lieutenant Nyota Uhura informed Captain James T. Kirk of an anomaly that Arex had been tracking on Delta Theta III, which was several thousand kilometers west of the landing party's position. (TAS: "Bem")

In 1986, Spock reported that the HMS Bounty was moving towards the west coast of North America (i.e. San Francisco). (Star Trek IV: The Voyage Home)

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